Effects of Pharmacologically Manipulated Amplitude and Starting Point on Edinger-Westphal–Stimulated Accommodative Dynamics in Rhesus Monkeys
نویسندگان
چکیده
منابع مشابه
Edinger-Westphal and pharmacologically stimulated accommodative refractive changes and lens and ciliary process movements in rhesus monkeys.
During accommodation, the refractive changes occur when the ciliary muscle contracts, releasing resting zonular tension and allowing the lens capsule to mold the lens into an accommodated form. This results in centripetal movement of the ciliary processes and lens edge. The goal of this study was to understand the relationship between accommodative refractive changes, ciliary process movements ...
متن کاملEdinger--Westphal stimulated accommodative dynamics in anesthetized, middle-aged rhesus monkeys.
The relationships between peak velocity and amplitude of Edinger-Westphal (EW) stimulated accommodation and disaccommodation were investigated in anesthetized, middle-aged rhesus monkeys. Accommodative responses were recorded at 30Hz with infrared photorefraction. Peak velocity of accommodation and disaccommodation increased linearly with stimulus amplitude. Peak velocities of accommodation con...
متن کاملDynamics of accommodative fatigue in rhesus monkeys and humans
Changes in accommodative dynamics with repeated accommodation were studied in three anesthetized rhesus monkeys and two conscious humans. Maximum accommodation was centrally stimulated via the Edinger-Westphal nucleus in monkeys with a 4 s on, 4 s off paradigm (4 x 4) for 17 min, 4 x 1.5 for 27 min and 2 x 1 for 16 min. Humans accommodated repeatedly to visual targets (5 x 5; 5D and 2 x 2; 6D) ...
متن کاملComparisons between pharmacologically and Edinger-Westphal-stimulated accommodation in rhesus monkeys.
PURPOSE Accommodation results in increased lens thickness and lens surface curvatures. Previous studies suggest that lens biometric accommodative changes are different with pharmacological and voluntary accommodation. In this study, refractive and biometric changes during Edinger-Westphal (EW) and pharmacologically stimulated accommodation in rhesus monkeys were compared. METHODS Accommodatio...
متن کاملAge-dependent loss of accommodative amplitude in rhesus monkeys: an animal model for presbyopia.
The refractive power and axial dimensions of the eye were measured under resting and fully accommodated conditions in 123 caged rhesus monkeys ranging in age from 0.5 to greater than 30 years. The mean resting refraction measured under ketamine anesthesia was -5 diopters. Accommodative amplitude, calculated as the difference between resting refraction and the most negative refraction measured 0...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2007
ISSN: 1552-5783
DOI: 10.1167/iovs.06-0380